These threads discuss the disordered physiological processes associated with disease or injury in a new and easier to way to understand. Check them out directly on Twitter here: #Pathophysiology
MedTweetorial: #Tweetorial
Author: @caseyalbin
Type: #Pathophysiology
Specialty: #Neurology #Neuro
Topics: #CranialNerve #MultipleCranialNeuorpathies #CranialNeuropathy
1/ Alright, #Neurotwitter, the votes for todayโs #neuroDDxThursday were overwhelmingly in favor of multiple cranial neuropathies!
Thought about one slide, but this needs a #tweetorial! So that you aren't ๐ฌ๐ฌ๐ฌ when confronted with this:
#MedEd #FOAMed @MedTweetorials
MedTweetorial: #Tweetorial
Author: @DrShmouni
Type: #Pathophysiology
Specialty: #FamilyMed #InternalMedicine #IM #Cardiology #CardioTwitter
Topics: #MonogenicHypertension #MolecularMechanisms #GordonSyndrome #LiddleSyndrome #ApparentMineralocorticoidExcess #GellerSyndrome

#endocation #endorules #endotips #endotwitter
๐ซMolecular mechanisms involved in the different types of monogenic hypertension (thread)๐
MedTweetorial: #Tweetorial
Author: @PacoDardon
Type: #Case #Pathophysiology
Specialty: #EmergencyMedicine #EM #CriticalCare
Topics: #Lactate #LacticAcid #Sepsis
ED 3 AM: ๐จ ambulance rushes in, pt in his 40's unconscious, BP 50/20, HR 140. Reanimation is started and arterial gases are ordered: lactate 10! Two hours later, pt conscious, MAP >65, HR 100, new arterial gases are ordered: lactate 9.
Was reanimation unsuccesful?
Poll & ๐งต:
MedTweetorial: #Tweetorial
Author: @amyaimei
Type: #Pathophysiology
Specialty: #Urology #Nephrology
Topics: #KidneyStones #Hypocitraturia #Citrate #RenalStones
The ๐ฉbaron of kidney stone prevention has been citrate supplementation.
๐Letโs quickly review hypocitraturia and its relationship to stones.
Where is most of your citrate reabsorbed?
MedTweetorial: #Tweetorial
Author: @WuidQ
Type: #Pathophysiology #Case
Specialty: #ID #InfectiousDisease #Orthopedics
Topics: #Osteomalacia #Osteoporosis #HIV #TenofovirDisoproxilFumarate #TDF #Hypophosphatemia #
52/M HIV (CD4 780 VL<20) on TDF/FTC/efavirenz w/ +b/l prox leg weakness, severe pain/tenderness ribs, back, hips, legs x 6 mos, requiring assistance. N/l Crea, โฌ๏ธCa โฌ๏ธALP. Hip XR: b/l pseudofractures fem neck. Spine XR: poor quality. W/c of the ff is needed to dx this condition?
MedTweetorial: #Tweetorial
Author: @PacoDardon
Type: #MedEd #Pathophysiology
Specialty: #GI #Gastroenterology #Neph #Nephrology #IM
Topics: #Cirrhosis #Albumin #AKI #HRS #Hepatorenal

Some days ago i had a pt with cirrhosis Child Pugh C admitted for AKI during my shift. Offending meds were withdrawn, IVC was seen at 0.9 cm and albumin infusion was started.
This common situation got my mind started: why is ๐ฅ so good for cirrhotic pts kidneys?
A brief ๐งต:
๐๐ฝ
MedTweetorial: #Tweetorial
Author: @iamnephrologist
Type: #Pathophysiology
Specialty: #Nephrology #Renal #Neph
Topics: #FoamyUrine #Frothuria

๐ฅWhat are causes of Foamy urine in absence of Proteinuriaโ๏ธ
#Tweetorial
๐กAny surfactant in urine can cause frothuriaโผ๏ธ
๐Surfactant has amphiphilic properties which helps trap pocket of gas in liquid and produce foam
Ref-CJASN
#NephroNotes #FOAMed #MedTwitter #MedEd
MedTweetorial: #Tweetorial
Author: @RosenelliEM @CuriousClinPod
Type: #MedEd #Pathophysiology
Specialty: #GI #Gastroenterology #Ophthalmology #Ophtho
Topics: #ConjunctivalIcterus #NotScleralIcterus #Jaundice
#ScleralIctures #EndScleralIcterus #Elastin #Sclera
A new @CuriousClinPod Ep is out!! A must listen to those who โฅ๏ธthe physical exam
Listen here๐below over follow the๐งต
http://curiousclinicians.com/2021/01/20/episode-17-why-does-bilirubin-deposit-in-the-eyes/
It's conjunctival, Not scleral icterus
#ConjunctivalIcterus #NotScleralIcterus #Jaundice
@AvrahamCooperMD @tony_breu @HannahRAbrams
MedTweetorial: #Tweetorial
Author: @mendesthiagob
Type: #MedEd #Pathophysiology
Specialty: #Endo #Endocrinology
Topics: #AmiodaroneInducedThyrotoxicosis #Iodine #Amiodarone #Thyrotoxicosis
Amiodarone-induced thyrotoxicosis is a dangerous and often subtle situation that occurs in 3-5% of patients, typically 4-36 months after initiating therapy.
Why does it occur? High-iodine content (37%).
Do not miss it! Follow the ๐งต (1/4)
#MedEd #tweetorials #MedTwitter
MedTweetorial: #Tweetorial
Author: @theABofPharmaC
Type: #MedEd #GraphicMed #Pathophysiology
Specialty: #Dermatology #Derm #MedDerm
Topics: #Pharmacology #HypersensitivitySyndromes #SJS #DRESS #TENS #ToxicEpidermalNecrolysis #StevensJohnsonSyndrome #DrugRashwithEosinophilia

How to remember ๐ง drugs that โคด๏ธrisk of skin hypersensitivity syndromes (SJS, DRESS, TENS)? ๐ง
Back to med chem days! ๐ฉ๐ปโ๐ฌ
Letโs start with anticonvulsants ๐
๐กAnticonvulsants with AROMATIC side chains = โคด๏ธ risk โ ๏ธ
โผ๏ธโฌ๏ธOffenders: see ๐ธ below
#TwitteRx #PharmICU๐งต 1/5
MedTweetorial: #Tweetorial
Author: @ElieNaddaf3
Type: #MedEd #Pathophysiology
Specialty: #CriticalCare #InfectiousDisease #ID
Topics: #CriticalIllnessMyopathy #Myopathy #CIM #COVID #COVID19

Since #COVID hit, we're hearing a lot about critical illness #myopathy (CIM). Follow this tweetorial that will cover the basic aspect of CIM. Photos below are from a patient with COVID-related CIM.
MedTweetorial: #Tweetorial
Author: @EmmGeezee
Type: #MedEd #Pathophysiology
Specialty: #GI #Gastroenterology #Pulm #Pulmonology
Topics: #IBD #Crohns #UC #UlcerativeColitis #PulmonaryManifestationsOfIBD
Man these past 24 hours have been... a lot, to say the least. Thank you so much to @CPSolvers for acknowledging it, encouraging reflection, & giving us an hour of peace & positivity w/ #VMR today. I discussed pulmonary manifestations of IBD... here are some highlights... ๐ซ๐ค 1/
MedTweetorial: #Tweetorial
Author: @AmitGoyalMD
Type: #Pathophysiology #MedEd
Specialty: #Endocrinology #Endo
Topics: #PrimaryAldosteronism #Aldo #Aldosterone #Renin #ARR #AldoReninRatio #SecondaryHypertension #HTN #Hypertension

How often do you check for Primary Aldosteronism (PA)?
Chances are, NOT nearly often enough!
VA study reveals widespread undertesting...can we do better?
https://www.acpjournals.org/doi/10.7326/M20-4873
If you've seen 10 pt's with HTN โก๏ธ you've probably seen PA!
Let's review in this #medtweetorial
MedTweetorial: #Tweetorial
Author: @eliekozaily1
Type: #MedEd #Pathophysiology
Specialty: #Pulm #Pulmonology #Cardiology #Cards
Topics: #PleuralEffusion #CHF #PericardialEffusions
1/ ๐ซx๐ซ
-Pleural effusions w/ CHF occur bilaterally, historically โmore common on the R sideโ?
-Do patients w/ CHF tend to sleep in the R lateral decubitus (RLD)?
-Pericardial effusions uncommon w/ CHF?
#MedTwitter #Cardiotwitter #MedEd
MedTweetorial: #Tweetorial
Author: @farid__jalali
Type: #Pathophysiology
Specialty: #InfectiousDisease #ID
Topics: #COVID19 #P๐น๐ฎ๐๐ฒ๐น๐ฒ๐A๐ฐ๐๐ถ๐๐ฎ๐๐ถ๐ผ๐ป #P๐๐น๐บ๐ผ๐ป๐ฎ๐ฟ๐E๐ป๐ฑ๐ผ๐๐ต๐ฒ๐น๐ถ๐ฎ๐นD๐ฒ๐๐๐ฎ๐ฏ๐ถ๐น๐ถ๐๐ฎ๐๐ถ๐ผ๐ป #S๐ฒ๐ฟ๐ผ๐๐ผ๐ป๐ถ๐ปI๐ป๐ต๐ถ๐ฏ๐ถ๐๐ถ๐ผ๐ป #SSRI

Proper attention to ๐ฎ๐น๐น aspects of pathology in COVID19, simultaneously, is paramount to proper treatment:
๐ฅpulmonary endothelium
โฌ๏ธโฌ๏ธ
๐ฅplatelets
Products of platelet-endothelial activation:
โก๏ธthrombi
โก๏ธplatelet-derived mediators
MedTweetorial: #Tweetorial
Author: @Dr_Brian_Cox
Type: #Pathophysiology #MedEd
Specialty: #Pathology
Topics: #Spleen #SplenicMass #LittoralCellAngioma #CD68 #SplenicVascularNeoplasm


Splenic mass in a 48-year-old female.
MedTweetorial: #Tweetorial
Author: @admit_medics
Type: #MedEd #Pathophysiology
Specialty: #Pediatrics #Peds #IM #InternalMedicine
Topics: #Hypocalcemia #Hypoparathyroidism #22q112deletionsyndrome #BernardSoulierSyndromeCATCH22
Youโre the medical registrar on-call and receive a call from the psychiatry SHO as a patient has an adjusted calcium of 1.76.
MedTweetorial: #Tweetorial
Author: @Dr_Brian_Cox
Type: #MedEd #Pathophysiology
Specialty: #Oncology #HemeOnc
Topics: #WarburgEffect #TCAcycle #CancerCells #LacticAcid #OttoWarburg #Glycolysis #CancerMetabolism #Cancer

1/
In 1920, Dr. Otto Warburg wrote the best grant request ever: "Request. I need 10,000 Mark."
MedTweetorial: #Tweetorial
Author: @ebtapper
Type: #Med #Pathophysiology
Specialty: #GI #Gastroenterology
Topics: #Ascites #Diuretics #LIverDisase

1/
WHERE does ascites come from?
HOW do diuretics treat ascites?
ARE you ready for a #tweetorial?
#livertwitter #medtwitter #MedEd
MedTweetorial: #Tweetorial
Author: @TylerLarsenMD
Type: #Pathophysiology
Specialty: #Cardiology #CardioTwitter
Topics: #BNP #Obesity #NTproBNP

1/
Why does obesity cause a "falsely low" B-type natriuretic peptide (BNP) in patients with heart failure?
I often hear this used to explain unexpectedly low BNP results, but I've never really understood why.
Let's explore in a #tweetorial.
#medtwitter #cardiotwitter
MedTweetorial: #Tweetorial
Author: @AARazmjou
Type: #Pathophysiology
Specialty: #Heme #Hematology #Rheumatology
Topics: #Thrombocytopenia #SLE #ITP #Lupus
1/8
What is the pathogenesis of thrombocytopenia in SLE/ITP (<100,000)? ๐ฉธ๐ฉธ๐ฉธ
First you should consider if this is straight antibody mediated (type II hypersensitivity, ie from SLE), versus another process:
๐ธTTP/HUS
๐ธAnti-phospholipid syndrome
๐ธDIC
๐ธHLH
๐ธMedications
MedTweetorial: #Tweetorial
Author: @nsrosenberg
Type: #MedEd #Pathophysiology
Specialty: #Pulmonology #Pulm
Topics: #UlcerativeBronchiolitis
Another new diagnosis I had never heard of until this pulm rotation: Ulcerative Bronchiolitis (yup, you saw that right). ๐งตof an illness script of a rare condition!
Inspired by @EmmGeezee's comments here
https://twitter.com/EmmGeezee/status/1324928165207216128?s=20
#MedTwitter #tweetorial
MedTweetorial: #Tweetorial
Author: @NEPHKIDS1
Type: #MedEd #Pathophysiology
Specialty: #Nephrology #Renal #Neph #Pediatrics #Peds
Topics: #Dehydration
#NEPHTWEETORIAL #NEPHKIDS2020 LET'S TALK DEHYDRATION!๐ฅต Welcome to our first tweetorial where we'll be discussing the pathophysiology of dehydration๐คฏ& try and answer the WHAT, WHY, WHERE, WHEN, HOW in management.๐ค -@jpsugumar @IPNA_PedNeph