These threads discuss the disordered physiological processes associated with disease or injury in a new and easier to way to understand. Check them out directly on Twitter here: #Pathophysiology
MedTweetorial: #Tweetorial
Author: @nihardesai7
Type: #MedEd #Pathophysiology
Specialty: #Hematology #IM #InternalMedicine
Topics: #Ferritin
#FERRITIN is being widely ordered these days. Let's dive into the details and learn more about this protein. A short thread for those interested. Covers some history, biology and practical aspects about FERRITIN.
1/n
MedTweetorial: #Tweetorial
Author: @RosenelliEM
Type: #MedEd #Pathophysiology
Specialty: #EmergencyMedicine #EM #InternalMedicine #IM
Topics: #DLacticAcidosis #Dla #Dlacatic #D_LacticAcid #LacticAcidosis #GastricBypass
If you all have not checked out @UnremarkableLab (https://www.youtube.com/channel/UCVQ3Na5zXk5lpdUfPKhZ_Ew) with @medrants I highly recommend it.
This past week we went through a great case on a patient who presented with neurological symptoms following a Gastric Bypass.
A short 🧵on D-lactic acidosis
MedTweetorial: #Tweetorial
Author: @CHESTCritCare
Type: #Pathophysiology #MedEd
Specialty: #CriticalCare
Topics: #LacticAcidosis #LacticAcid #Lacate
Where does lactate come from and how to approach elevated lactate levels: a 🧵
@accpchest #CHESTCritCare
MedTweetorial: #Tweetorial
Author: @VijayanMD
Type: #MedEd #Pathophysiology
Specialty: #Neph #Nephrology #EmergencyMedicine
Topics: #TXA #TranexamicAcid #TXAToxicity #ESRD #MedicationToxicityInCKD
1/Medication toxicity in CKD
Pt with ESRD, on in-center HD presents with acute MS changes. Thorough eval by neuro. No baclofen- (@Nephro_Sparks) but noted to be on tranexamic acid 650 tid for chronic GI bleed.
Short🧵
MedTweetorial: #Tweetorial
Author: @caseyalbin
Type: #Physiology #Pathophysiology #MedEd #case
Specialty: #Neurology #Neuro
Topics: #Stroke #CardiacArrest #LateralWallenbergSyndrome #CentralHypoventilationSyndrome #CHS #OndinesCurse #WallenbergSyndrome
A #tweetorial #medtweetorial
@MedTweetorials
1/
3 AM: Pager Pager Pager
Me [very groggily]: Hey, what’s up?
Awesome overnight APP: Sorry to wake you! But, Mrs. Very-Small-Stroke-NIHSS-2-Had-Been-Clinically-Stable-All-Day just PEA arrested.
Me [not so groggily]:
MedTweetorial: #Tweetorial
Author: @AvrahamCooperMD
Type: #Pathophysiology #MedEd
Specialty: #Anesthesiology
Topics: #Propofol #PropofolRelatedInfusionSyndrome #PRIS
1/ 🧵
Why can propofol infusion at high doses cause Propofol-related Infusion Syndrome (PRIS)?
To understand why we have to revisit the old adage of supply and demand.
#Tweetorial #MedTwitter
MedTweetorial: #Tweetorial
Author: @rav7ks
Type: #Pathophysiology #MedEd
Specialty: #InfectiousDisease #ID
Topics: #Hypothermia #Sepsis #IL10 #IL1 #IL6 #TNF #Cytokines #AntiInflammatoryCytokineRelease
1/8 Why can an infection cause hypothermia ? Great question from my MS3 last week. My reaction was " I have no idea but we can look it up "
So why does it exactly happen and why is it important not to simply brush this finding aside !
#MedTwitter #MedStudentTwitter #FOAMed
MedTweetorial: #Tweetorial
Author: @ebtapper
Type: #Pathophysiology
Specialty: #Gastroenterology #GI
Topics: #GGT #GammaGlutamylTtransferase
1/
WHAT the heck is GGT?
#tweetorial #livertwitter #medtwitter
MedTweetorial: #Tweetorial
Author: @tony_breu
Type: #Pathophysiology #MedEd
Specialty: #GI #Gastroenterology
Topics: #AlkalinePhosphatase #AlkPhos #ALP #BiliaryObstruction
1/11
Why is alkaline phosphatase elevated in biliary obstruction?
This question was debated for decades. The current explanation is NOT what I had expected.
Will you be surprised too?
MedTweetorial: #Tweetorial
Author: @tony_breu
Type: #Pathophysiology
Specialty: #Nephrology #Renal #Neph #Rheumatology
Topics: #ACEInhibitors #ACE #Scleroderma #SclerodermaRenalCrisis
1/12
Why do we use ACE inhibitors in scleroderma renal crisis?
I learned this early in training but never understood why these drugs were so game-changing.
Let's have a look.
MedTweetorial: #Tweetorial
Author: @ebtapper
Type: #MedEd #Pathophysiology
Specialty: #Gastroenterology #GI
Topics: #Cirrhosis #PalmarErythema #Estrogen #LiverDisease #Spironolactone #Testosterone
1/
WHY does #cirrhosis cause palmar erythema?
HOW is estrogen involved?
WHO is ready for a #tweetorial?
Let's talk hormones, the liver, the impact of imbalanced testosterone/estrogen, & the history of spironolactone
#livertwitter #medtwitter #MedEd
MedTweetorial: #Tweetorial
Author: @apsmunro
Type: #MedEd #Pathophysiology
Specialty: #InfectiousDisease #ID
Topics: #Fever #FeverHistory #FeverMythBusting
1/15 #Fever #tweetorial
Parents and paediatricians alike are obsessed with fever
We've all got fever fever 🔥 But it is SO misunderstood
Let's take a look at what fever actually is, and finish off with some myth busting!
#FOAMPed #FOAMed #IDTwitter #PedsICU #PedsID
MedTweetorial: #Tweetorial
Author: @tony_breu
Type: #MedEd #Pathophysiology
Specialty: #InfectiousDisease #ID
Topics: #Fever #BenefitsOfFever #FeverEtiology
1/14
How does fever help us fight infections?
For millennia, fever has been recognized as a beneficial response to invading pathogens.
If this is so, why don't we have a resting temperature of 102°F (38.9°C)? Wouldn't that protect us even better?
Let's have a look.
MedTweetorial: #Tweetorial
Author: @AvrahamCooperMD
Type: #MedEd #Pathophysiology
Specialty: #Pulmonology #Pulm #OBGYN #OB #GYN
Topics: #CatamenialPneumothorax #Pneumothorax
1/🧵
Why does catamenial pneumothorax (pneumothorax that recurs with menstruation) almost always occur on the right side?
Why doesn't it affect both sides of the chest equally?
#medtwitter #tweetorial
MedTweetorial: #Tweetorial
Author: @aishaikh
Type: #MedEd #Pathophysiology
Specialty: #InternalMedicine #IM #Rheumatology #Rheum
Topics: #Cryoglobulinemia #Cryoglobulins
#CryoglobulinemiaVasculitis
💥 Tweetorial on ‘Cryoglobulinemia’
⚡️What are Cryoglobulins?
⚡️When should a clinician suspect Cryoglobulinemia & Cryoglobulinemia vasculitis?
⚡️How to establish the diagnosis?
⚡️Significance of Rheumatoid Factor
1/
@GlomCon
#Onconephrology
MedTweetorial: #Tweetorial
Author: @caseyalbin
Type: #Pathophysiology
Specialty: #Neurology #Neuro
Topics: #CranialNerve #MultipleCranialNeuorpathies #CranialNeuropathy
1/ Alright, #Neurotwitter, the votes for today’s #neuroDDxThursday were overwhelmingly in favor of multiple cranial neuropathies!
Thought about one slide, but this needs a #tweetorial! So that you aren't 😬😬😬 when confronted with this:
#MedEd #FOAMed @MedTweetorials
MedTweetorial: #Tweetorial
Author: @DrShmouni
Type: #Pathophysiology
Specialty: #FamilyMed #InternalMedicine #IM #Cardiology #CardioTwitter
Topics: #MonogenicHypertension #MolecularMechanisms #GordonSyndrome #LiddleSyndrome #ApparentMineralocorticoidExcess #GellerSyndrome
#endocation #endorules #endotips #endotwitter
🫀Molecular mechanisms involved in the different types of monogenic hypertension (thread)👇
MedTweetorial: #Tweetorial
Author: @PacoDardon
Type: #Case #Pathophysiology
Specialty: #EmergencyMedicine #EM #CriticalCare
Topics: #Lactate #LacticAcid #Sepsis
ED 3 AM: 🚨 ambulance rushes in, pt in his 40's unconscious, BP 50/20, HR 140. Reanimation is started and arterial gases are ordered: lactate 10! Two hours later, pt conscious, MAP >65, HR 100, new arterial gases are ordered: lactate 9.
Was reanimation unsuccesful?
Poll & 🧵:
MedTweetorial: #Tweetorial
Author: @amyaimei
Type: #Pathophysiology
Specialty: #Urology #Nephrology
Topics: #KidneyStones #Hypocitraturia #Citrate #RenalStones
The 🎩baron of kidney stone prevention has been citrate supplementation.
📖Let’s quickly review hypocitraturia and its relationship to stones.
Where is most of your citrate reabsorbed?
MedTweetorial: #Tweetorial
Author: @WuidQ
Type: #Pathophysiology #Case
Specialty: #ID #InfectiousDisease #Orthopedics
Topics: #Osteomalacia #Osteoporosis #HIV #TenofovirDisoproxilFumarate #TDF #Hypophosphatemia #
52/M HIV (CD4 780 VL<20) on TDF/FTC/efavirenz w/ +b/l prox leg weakness, severe pain/tenderness ribs, back, hips, legs x 6 mos, requiring assistance. N/l Crea, ⬇️Ca ⬆️ALP. Hip XR: b/l pseudofractures fem neck. Spine XR: poor quality. W/c of the ff is needed to dx this condition?
MedTweetorial: #Tweetorial
Author: @PacoDardon
Type: #MedEd #Pathophysiology
Specialty: #GI #Gastroenterology #Neph #Nephrology #IM
Topics: #Cirrhosis #Albumin #AKI #HRS #Hepatorenal
Some days ago i had a pt with cirrhosis Child Pugh C admitted for AKI during my shift. Offending meds were withdrawn, IVC was seen at 0.9 cm and albumin infusion was started.
This common situation got my mind started: why is 🥚 so good for cirrhotic pts kidneys?
A brief 🧵:
👇🏽
MedTweetorial: #Tweetorial
Author: @iamnephrologist
Type: #Pathophysiology
Specialty: #Nephrology #Renal #Neph
Topics: #FoamyUrine #Frothuria
🔥What are causes of Foamy urine in absence of Proteinuria⁉️
#Tweetorial
💡Any surfactant in urine can cause frothuria‼️
👉Surfactant has amphiphilic properties which helps trap pocket of gas in liquid and produce foam
Ref-CJASN
#NephroNotes #FOAMed #MedTwitter #MedEd
MedTweetorial: #Tweetorial
Author: @RosenelliEM @CuriousClinPod
Type: #MedEd #Pathophysiology
Specialty: #GI #Gastroenterology #Ophthalmology #Ophtho
Topics: #ConjunctivalIcterus #NotScleralIcterus #Jaundice
#ScleralIctures #EndScleralIcterus #Elastin #Sclera
A new @CuriousClinPod Ep is out!! A must listen to those who ♥️the physical exam
Listen here👇below over follow the🧵
http://curiousclinicians.com/2021/01/20/episode-17-why-does-bilirubin-deposit-in-the-eyes/
It's conjunctival, Not scleral icterus
#ConjunctivalIcterus #NotScleralIcterus #Jaundice
@AvrahamCooperMD @tony_breu @HannahRAbrams
MedTweetorial: #Tweetorial
Author: @mendesthiagob
Type: #MedEd #Pathophysiology
Specialty: #Endo #Endocrinology
Topics: #AmiodaroneInducedThyrotoxicosis #Iodine #Amiodarone #Thyrotoxicosis
Amiodarone-induced thyrotoxicosis is a dangerous and often subtle situation that occurs in 3-5% of patients, typically 4-36 months after initiating therapy.
Why does it occur? High-iodine content (37%).
Do not miss it! Follow the 🧵 (1/4)
#MedEd #tweetorials #MedTwitter