COVID-19

#Social

After caring for patients in the ICU with #COVID for the last week, the time seems right for a #pulmonology #tweetorial on #Proning or #PronePositioning  #Pathophysiology #MedEd #InfectiousDisease #ID #Pulm #pulmonology  #CriticalCare #ICU #COVID19 #coronavirus #nCoV19 #Proning  #PronePositioning
Do you want to learn the mechanisms of the drugs being tested for #COVID-19 (aka SARS-CoV-2)? The WHO has launched the SOLIDARITY trial, rapidly testing 4 treatment regimens.
#MedEd #Research #InfectiousDisease #ID #Pharmacology #COVID19 #nCoV19 #coronavirus #SARSCoV2 #Lopinavir #remdesevir #Hydroxychloroquine #InterferonBeta
Let’s talk about school closures re COVID-19. It’s a tough topic, scientifically and pragmatically. It’s hard to estimate the benefits precisely. And closing schools can have costs, such as health care workers having to stay home, kids missing subsidized  #MedEd #InfectiousDisease #ID #SchoolClosure #COVID19 #nCoV19 #coronavirus #NPI #NonPharmacologicalIntervention
Let’s talk about the fact that both the attack rate and the death rate among the young is indeed very low with COVID19, unlike most prior pandemics. And let’s speculate about some of the biological reasons. #HistMed #MedEd #InfectiousDisease #ID #attackrate #deathrate #COVID19 #nCoV19 #coronavirus #CaseFatalityRate #sCFR #infectionfatalityrate #IFR
Have you ever wondered how a vaccineSyringe is made and how long it takes before it reaches your arm Flexed biceps? #medtwitter #tweetorial #NKFClinicals #COVID19 #MedEd  #InfectiousDisease #ID #Pharmacology #COVID19 #coronavirus #nCoV19 #Vaccines #vaccination
#COVID19 Thread: my first case of acute #Hydroxychloroquine intoxication. How do you manage it? Here is what I learned and useful resources I would like to share for your next case, as this presentation may become common.   #Pathophysiology #MedEd #Case   #InfectiousDisease #ID #Toxicology #Pharmacology #COVID19 #coronavirus #nCoV19 #Hydroxychloroquine #HydroxychloroquineIntoxication
talk about #COVID-19 literature update today  #Pathophysiology #MedEd #Lecture #InfectiousDisease #ID #COVID19 #coronavirus #nCoV19
With an exponential rise in COVID cases, it’s time to talk about how to avoid running out of ventilators.  NYC is encountering this now, and other locales will follow shortly.  ICU resources (especially invasive ventilation) are unfortunately finite #MedEd #Advocacy #CriticalCare #Pulmonology #Pulm #COVID19 #nCoV2019 #coronavirus #Ventilators #NYC #ICU #VentilatorShortage
Let’s talk about what happens if you get COVID19 and recover. Are you immune to the disease? How long does the immunity last? And what does that mean for your life and for the public health and economy of our society? #Pathophysiology #Immunology #InfectiousDisease #ID #COVID19 #nCoV19 #coronavirus #Immunity #Immunization
Clinical Question: Hydroxychloroquine (HCQ) is used against malaria and autoimmune diseases, and new data suggest it may be effective against CoVID-19. What exactly is CQ, how does it work against so many different diseases? #Pathophysiology #InfectiousDisease #ID #Pharmacology #COVID19 #nCoV19 #coronavirus #HCQ #Hydroxychloroquine
Feeling overwhelmed by the #COVID19 #SARSCoV2 literature? Me too. We’re in this together. I’ll show you #HowIReadThisPaper and my appraisal. Add, comment, and correct me where I am wrong. #Publication #InfectiousDisease #ID #COVID19 #SARSCoV2 #NEJM #HowIReadThisPaper #CoronaVirusChina
SARS-CoV-2 and the RAAS System Curious about the role of ACE2 in the pathophysiology of #COVID19? Read on!  #Pathophysiology #Cardiology #CardioTwitter #InfectiousDisease #ID #COVID19 #SARSCoV2 #RAAS #ACE2 #nCO#coronavirus
As the #COVID19 pandemic progresses, exactly why men get infected more frequently, and with greater severity, than women is unknown. This #tweetorial examines a theory (emphasis on theory) that might explain some of this difference. #MedEd #Question #Publication #Pathophysiology #InfectiousDisease #ID #COVID19 #Coronavirus #GenderDifferences #GenderTheory #ACE2 #Smoking #TobaccoUse

SARS-CoV-2 infected host cell proteomics reveal potential therapy targets.

Following requests, my first #tweetorial on our recent preprint Relevant: #COVID19, #SARSCOV2, #coronavirus, #COVIDー19, #COVID_19, #infection, #proteomics, #massspec, #Science

#Research #InfectiousDisease #ID #COVID19, #SARSCOV2, #coronavirus, #COVIDー19, #COVID_19 #infection, #proteomics #massspec #Science
APRV in the time of Corona: Heavy check markPts w/ COVID-19 may have hypoxia refractory to “normal” ventilator settings.Heavy check markAPRV is a ventilator mode that may benefit this population.    #Physiology #CriticalCare #Pulmonology #Pulm #COVID19 #Coronavirus #ventsetting #hypoxia #APRV #refratoryhypoxia
There’s a lot of talk about *potentially* using hydroxychloroquine to treat COVID. This is the most relevant I’ve been in weeks, so here’s a thread which addresses HCQ  ssociated retinal toxicity #MedEd #Pharmacology #Ophthalmology #Optho #InfectiousDisease #ID #Hydroxychloroquine #COVID #COVID19 #coronavirus #retinaltoxicity #HCQRetinalToxicity
We’ve been in full #COVID19 mode in my hospital in Alcorcón (Madrid), Spain for the past 2 weeks.  This crisis has forced us to adapt like we never thought possible. Here’s how we’re doing that on our units, in hope that it’ll help others across the globe #MedEd #COVID19 #coronavirus #nCoV2019 #HospitalPreparation #PPE #FOAMcovid
Tweetorial of heart-lung interactions in the setting of mechanical ventilation (MCV) from @cardionerds episode 20. These concepts will apply to critically ill COVID-19 patients that are developing concurrent respiratory and cardiac failure. #Pathophysiology #Cardiology #CardioTwitter #CriticalCare #COVID19 #coronavirus #mechanicalventilation #RespiratoryFailure #CardiacFailure #RespiratoryDistress #Hemodynamics #LVFailure #RVFailure #CardioNerds
A serological assay to detect SARS-CoV-2 seroconversion in humans #MedEd #InfectiousDisease #ID #Immunology #COVID19 #nCoV19 #Coronavirus #immunity #Vaccine #COVIDVaccine #Antibodies
Let’s talk about what happens if you get COVID19 and recover. Are you immune to the disease? How long does the immunity last? And what does that mean for your life and for the public health and economy of our society?  #MedEd #InfectiousDisease #ID #Immunology #COVID19 #nCoV19 #Coronavirus #immunity #Vaccine #COVIDVaccine
Tips on the mechanically ventilated ARDS and sick hypoxemic patient.  Protect the lungs from the start!  #Physiology  #Pulmonology #Pulm #CriticalCare #ARDS #Ventilator  #Hypoxemia #MechanicalVentilation
Anxiety amidst #COVID19: A teen asked if I could up their SSRI dose. They had well-managed anxiety, but something changed. “They’re anxious about coronavirus”, #MedEd #Pediatrics #Peds #Psychiatry #Psych #Anxiety #anxiety #SSRI #COVID19
I get it. You’re young, you’re healthy, and you’re not worried about #COVID19. Give me a chance to tell you why you should be in this #tweetorial. #MedEd #InfectiousDisease #ID #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus #nCOV
A thread of information, my interpretation, links to sources & predictions of COVID19 #MedEd #Pathophysiology #InfectiousDisease #ID #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus #nCOV #COVID19Treatement
Latest tweetorial: ICU vent management for dummies. #MedEd #Physiology #InfectiousDisease #ID #Pulmonology #Pulm #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus #nCOV #ARDS #ICUVentManagement #VentManagement
Creative solutions as published in @JAMA_current #MedEd #Pathophysiology #InfectiousDisease #ID #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus #nCOV @JAMA_current #Taiwan #CreativeSolutions @WHO
First review of #COVID19 and the kidney #MedEd #Pathophysiology #InfectiousDisease #ID #Nephrology #Renal #Neph #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus #nCOV #nephjc
A front line account of COVID from a front-line ICU physician in a Seattle hospital #MedEd #Advocacy #InfectiousDisease #ID #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus #nCOV
Why does soap work so well on the SARS-CoV-2, the coronavirus and indeed most viruses? #MedEd #Pathophysiology #InfectiousDisease #ID #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus #nCOV
Each day we learn more about the #nCOV2019 outbreak. Here is a #tweetorial on 5 key questions and terminology in infectious disease epidemiology to help make sense of all of this information. #MedEd #Epidemiology #InfectiousDisease #ID #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus #nCOV
Because #COVID19 / #coronavirus is so hot right now, here’s a little #tweetorial on How To Emotionally Not Explode During Pandemic 2019 (and Survive!) #MedEd #InfectiousDisease #ID #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus
On behalf of Chest Infections Network, it is my pleasure to present following information on #COVID19. #MedEd #InfectiousDisease #ID #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus
What do ground glass opacities (GGO) look like? #Pathophysiology #GraphicMed #Case #Radiology #Rads #GGO #GroundGlassOpacities
Need-to-know updates re: COVID from the experts, courtesy of infectious disease grand rounds @UCSF_ID #MedEd #Pathophysiology #ID #InfectiousDisease #COVID19 #coronavirus #CoronaOutbreak
There are Two major types of COVID-19 L Type and S Type #MedEd #ID #InfectiousDisease #COVID19 #coronavirus #CoronaOutbreak
Notes from the front lines on COVID19: Sharing from another physician From an ID conference in Californi #MedEd #InfectiousDisease #ID #IDAC #COVID19 #coronavirus
the @ASNKidney did a webinar on COVID-19. I highly recommend it. I am going to do a #Tweetorial covering the high points. #MedEd #Pathophysiology #InfectiousDisease #ID #Nephrology #Renal #Neph #COVID19 #coronavirus #CoronavirusOutbreak #Coronavirus #nCOV
It’s time to clear up the issues about testing. So I’ve put together a #COVID19 thread on spread. Addressing the Super-spreaders, Spreaders, and the essentiality of testing #MedEd #InfectiousDisease #ID #COVID19 #coronavirus #nCoV2019 #superspreader #CovidTesting #Covid19testing
#COVID19 treatment protocols to tackle antiviral and hyperinflammation pathoimmunology #MedEd #InfectiousDisease #ID #Pharmacology #COVID19 #coronavirus #nCoV19 #COVID19Treatment
the most informative analysis of more than 25,000 #COVID19 cases in Wuhan that I’ve seen. Here are some key lessons (none of which we are following in the US). #MedEd #Pathophysiology #InfectiousDisease #ID #COVID19 #coronavirus #nCoV19
What is ACE2? We’ve been hearing about it a lot because of #coronavirus and its implications with hypertension and ACE-I and ARBS. As it turns out, my college research gig was in ACE2. #MedEd #Pathophysiology #Pharmacology #InfectiousDisease #ID #Cardiology #cardiotwitter #COVID19 #coronavirus #nCoV19 #ACEi #ACEinhibitors #ACE2
What can history, if anything, teach us about #Covid_19 ? What pathogen was responsible for a global pandemic in 1918? #MedEd #HistMed #InfectiousDisease #ID #COVID19 #coronavirus #nCoV19
Do NSAIDs (ibuprofen, naproxen, etc.) somehow worsen coronavirus infection? Lots of people asking this question. #MedEd #Pathophysiology #InfectiousDisease #ID #Nephrology #Renal #Neph #COVID19 #coronavirus #nCoV19 #NSAIDS #Pharmacology
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